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NR0B2 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00008431-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-NR0B2 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 28.1
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-NR0B2 antibody (H00008431-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00008431-T01
    NR0B2 transfected lysate.
    Western Blot
    QC Testing of H00008431-T01
    Lane 1: NR0B2 transfected lysate ( 28.1 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 8431
  • Protein Accession#:
  • -
  • Gene Name:
  • NR0B2
  • Gene Alias:
  • FLJ17090,SHP,SHP1
  • Gene Description:
  • nuclear receptor subfamily 0, group B, member 2
  • Gene Summary:
  • The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000004414,orphan nuclear receptor SHP,short heterodimer partner,small heterodimer partner
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