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Last updated: 2016/10/23
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NR0B2 monoclonal antibody (M01), clone 1A11

  • Catalog # : H00008431-M01
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a full length recombinant NR0B2.
  • Immunogen:
  • NR0B2 (AAH30207, 1 a.a. ~ 257 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Isotype:
  • IgG2a Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • NR0B2 monoclonal antibody (M01), clone 1A11. Western Blot analysis of NR0B2 expression in human colon.
  • PDF DownloadProtocol Download
  • Sandwich ELISA (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
  • Detection limit for recombinant GST tagged NR0B2 is approximately 3ng/ml as a capture antibody.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
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  • Sandwich ELISA (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8431
  • Gene Name:
  • NR0B2
  • Gene Alias:
  • FLJ17090,SHP,SHP1
  • Gene Description:
  • nuclear receptor subfamily 0, group B, member 2
  • Gene Summary:
  • The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000004414,orphan nuclear receptor SHP,short heterodimer partner,small heterodimer partner
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