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LTBP4 Pre-design Chimera RNAi

  • Catalog # : H00008425-R03
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Homo sapiens latent transforming growth factor beta binding protein 4 (LTBP4), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_003573
  • Target Region:
  • Coding sequence
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 8425
  • Gene Name:
  • LTBP4
  • Gene Alias:
  • FLJ46318,FLJ90018,LTBP-4,LTBP-4L
  • Gene Description:
  • latent transforming growth factor beta binding protein 4
  • Gene Summary:
  • Transforming growth factor-beta, or TGFB (see TGFB1; MIM 190180), remains biologically latent after secretion, blocked from activity by its N-terminal propeptide (the latency-associated peptide, or LAP). TGFB is activated by its dissociation from LAP. The latent form of TGFB is secreted in association with a latent TGFB-binding protein, or LTBP (see LTBP1; MIM 150390), and assembled into the extracellular matrix. LTBPs are mainly composed of epidermal growth factor (EGF; MIM 131530)-like repeats and protein domains with 8-cysteine repeats, both of which are also found in fibrillins (e.g., MIM 134797). See Oklu and Hesketh (2000) [PubMed 11104663] for a review of the LTBP gene family.[supplied by OMIM
  • Other Designations:
  • latent transforming growth factor-beta binding protein 4L
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