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BBOX1 rabbit monoclonal antibody

  • Catalog # : H00008424-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human BBOX1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human BBOX1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human BBOX1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8424
  • GeneBank Accession#:
  • BBOX1
  • Gene Name:
  • BBOX1
  • Gene Alias:
  • BBH,BBOX,G-BBH,gamma-BBH
  • Gene Description:
  • butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
  • Gene Summary:
  • This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation. [provided by RefSeq
  • Other Designations:
  • gamma-butyrobetaine dioxygenase,gamma-butyrobetaine hydroxylase,gamma-butyrobetaine,2-oxoglutarate dioxygenase 1
  • Gene Pathway
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