BBOX1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human BBOX1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human BBOX1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human BBOX1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — BBOX1
Entrez GeneID
8424GeneBank Accession#
BBOX1Gene Name
BBOX1
Gene Alias
BBH, BBOX, G-BBH, gamma-BBH
Gene Description
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
Omim ID
603312Gene Ontology
HyperlinkGene Summary
This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation. [provided by RefSeq
Other Designations
gamma-butyrobetaine dioxygenase|gamma-butyrobetaine hydroxylase|gamma-butyrobetaine,2-oxoglutarate dioxygenase 1
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