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PLA2G6 rabbit monoclonal antibody

  • Catalog # : H00008398-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PLA2G6 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PLA2G6 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PLA2G6 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8398
  • Gene Name:
  • PLA2G6
  • Gene Alias:
  • CaI-PLA2,GVI,INAD1,IPLA2-VIA,PARK14,PLA2,PNPLA9,iPLA2
  • Gene Description:
  • phospholipase A2, group VI (cytosolic, calcium-independent)
  • Gene Summary:
  • The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only two of them have been determined to date. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000028877,calcium-independent phospholipase A2,cytosolic, calcium-independent phospholipase A2,patatin-like phospholipase domain containing 9,phospholipase A2, group VI
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