Immunoprecipitation of PLA2G6 transfected lysate using anti-PLA2G6 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with PLA2G6 purified MaxPab mouse polyclonal antibody (B01P) (H00008398-B01P).
The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only two of them have been determined to date. [provided by RefSeq
OTTHUMP00000028877,calcium-independent phospholipase A2,cytosolic, calcium-independent phospholipase A2,patatin-like phospholipase domain containing 9,phospholipase A2, group VI