MAD1L1 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human MAD1L1 partial ORF ( AAH09964, 619 a.a. - 718 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
KEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSSLTLELFSRQTVA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (85); Rat (85)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MAD1L1
Entrez GeneID
8379GeneBank Accession#
BC009964Protein Accession#
AAH09964Gene Name
MAD1L1
Gene Alias
HsMAD1, MAD1, PIG9, TP53I9, TXBP181
Gene Description
MAD1 mitotic arrest deficient-like 1 (yeast)
Gene Ontology
HyperlinkGene Summary
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
MAD1 (mitotic arrest deficient, yeast, homolog)-like 1|MAD1-like 1 protein|mitotic-arrest deficient 1, yeast, homolog-like 1|tumor protein p53 inducible protein 9
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Interactome
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Pathway
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Disease
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