HIST1H2AC (Human) Recombinant Protein (P01)
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More Files
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Specifications
Product Description
Human HIST1H2AC full-length ORF ( NP_003503.1, 1 a.a. - 130 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
40.5
Interspecies Antigen Sequence
Mouse (98); Rat (99)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — HIST1H2AC
Entrez GeneID
8334GeneBank Accession#
NM_003512.3Protein Accession#
NP_003503.1Gene Name
HIST1H2AC
Gene Alias
H2A/l, H2AFL, MGC99519, dJ221C16.4
Gene Description
histone cluster 1, H2ac
Omim ID
602794Gene Ontology
HyperlinkGene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq
Other Designations
H2A histone family, member L|OTTHUMP00000016145|histone 1, H2ac|histone H2AC
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