FZD8 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (36.01 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant FZD8.
Immunogen
FZD8 (NP_114072, 72 a.a. ~ 161 a.a) partial recombinant protein with GST tag.
Sequence
FWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRTDLTTAAP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.01 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — FZD8
Entrez GeneID
8325GeneBank Accession#
NM_031866Protein Accession#
NP_114072Gene Name
FZD8
Gene Alias
FZ-8, hFZ8
Gene Description
frizzled homolog 8 (Drosophila)
Omim ID
606146Gene Ontology
HyperlinkGene Summary
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq
Other Designations
OTTHUMP00000019454|frizzled 8
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Interactome
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Pathway
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Disease
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Publication Reference
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EXTRACELLULAR AND MEMBRANE-ASSOCIATED PROSTATE CANCER MARKERS.
George G. Klee, George Vasmatzis, Farhad Kosari, Eric W. Klee
United States Patent Application Publication 2010 Feb; [Epub].
Application：Array, Mammal, Prostate cancer.
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EXTRACELLULAR AND MEMBRANE-ASSOCIATED PROSTATE CANCER MARKERS.
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