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FZD6 Pre-design Chimera RNAi

  • Catalog # : H00008323-R02
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens frizzled homolog 6 (Drosophila) (FZD6), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_003506
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 8323
  • Gene Name:
  • FZD6
  • Gene Alias:
  • Hfz6
  • Gene Description:
  • frizzled homolog 6 (Drosophila)
  • Gene Summary:
  • This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • frizzled 6,seven transmembrane helix receptor
  • Related Disease
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