FZD4 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human FZD4 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — FZD4
Entrez GeneID
8322GeneBank Accession#
NM_012193.2Protein Accession#
NP_036325.2Gene Name
FZD4
Gene Alias
CD344, EVR1, FEVR, FZD4S, Fz-4, FzE4, GPCR, MGC34390
Gene Description
frizzled homolog 4 (Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq
Other Designations
WNT receptor frizzled-4|exudative vitreoretinopathy 1 (autosomal dominant; Criswick-Schepens syndrome)|frizzled 4
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Interactome
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Pathway
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Disease
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