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FZD4 rabbit monoclonal antibody

  • Catalog # : H00008322-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human FZD4 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human FZD4 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human FZD4 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8322
  • GeneBank Accession#:
  • FZD4
  • Gene Name:
  • FZD4
  • Gene Alias:
  • CD344,EVR1,FEVR,FZD4S,Fz-4,FzE4,GPCR,MGC34390
  • Gene Description:
  • frizzled homolog 4 (Drosophila)
  • Gene Summary:
  • This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq
  • Other Designations:
  • WNT receptor frizzled-4,exudative vitreoretinopathy 1 (autosomal dominant; Criswick-Schepens syndrome),frizzled 4
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