LAGE3 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human LAGE3 full-length ORF (AAH15744.2, 1 a.a. - 143 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MRDADADAGGGADGGDGRGGHSCRGGVDTAAAPAGGAPPAHAPGPGRDAASAARGSRMRPHIFTLSVPFPTPLEAEIAHGSLAPDAEPHQRVVGKDLTVSGRILVVRWKAEDCRLLRISVINFLDQLSLVVRTMQRFGPPVSR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
42.13
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — LAGE3
Entrez GeneID
8270GeneBank Accession#
BC015744.1Protein Accession#
AAH15744.2Gene Name
LAGE3
Gene Alias
CVG5, DXS9879E, DXS9951E, ESO3, ITBA2
Gene Description
L antigen family, member 3
Omim ID
300060Gene Ontology
HyperlinkGene Summary
This gene belongs to the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9. [provided by RefSeq
Other Designations
OTTHUMP00000032119|OTTHUMP00000061461
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