MKKS MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human MKKS protein.
Immunogen
MKKS (NP_061336.1, 1 a.a. ~ 570 a.a) full-length human protein.
Sequence
MSRLEAKKPSLCKSEPLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSSFSDCGLFTAILCCNLIENVQRLGLTPTTVIRLNKHLLSLCISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAEGHIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLSGDTSDTGEGTVVVSYGVSLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPSLKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSKHFFHLIPNEATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAYIRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHDGGEILTDMKYGHLWSVQADSPCVANWPDLLSQCGCGLYNSQEELNWSFLRSTRRPFVPQSCLPHEAVGSASNLTLDCLTAKLSGLQVAVETANLILDLSYVIEDKN
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (77); Rat (78)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MKKS MaxPab rabbit polyclonal antibody. Western Blot analysis of MKKS expression in A-431.Western Blot (Transfected lysate)
Western Blot analysis of MKKS expression in transfected 293T cell line (H00008195-T02) by MKKS MaxPab polyclonal antibody.
Lane 1: MKKS transfected lysate(62.30 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of MKKS transfected lysate using anti-MKKS MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with MKKS purified MaxPab mouse polyclonal antibody (B01P) (H00008195-B01P). -
Gene Info — MKKS
Entrez GeneID
8195GeneBank Accession#
NM_018848.2Protein Accession#
NP_061336.1Gene Name
MKKS
Gene Alias
BBS6, HMCS, KMS, MKS
Gene Description
McKusick-Kaufman syndrome
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with sequence similarity to the chaperonin family. The encoded protein may have a role in protein processing in limb, cardiac and reproductive system development. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6 and McKusick-Kaufman syndrome. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
McKusick-Kaufman syndrome protein|OTTHUMP00000030274
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Interactome
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Disease
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Publication Reference
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Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesis.
Rachel RA, May-Simera HL, Veleri S, Gotoh N, Choi BY, Murga-Zamalloa C, McIntyre JC, Marek J, Lopez I, Hackett AN, Zhang J, Brooks M, den Hollander AI, Beales PL, Li T, Jacobson SG, Sood R, Martens JR, Liu P, Friedman TB, Khanna H, Koenekoop RK, Kelley MW, Swaroop A.
The Journal of Clinical Investigation 2012 Apr; 122(4):1233.
Application:IP, Bovine, Retinal.
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Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesis.
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