SF3A2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human SF3A2 partial ORF ( NP_009096, 112 a.a. - 216 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
IGRPGYKVTKQRDSEMGQQSLLFQIDYPEIAEGIMPRHRFMSAYEQRIEPPDRRWQYLLMAAEPYETIAFKVPSREIDKAEGKFWTHWNRETKQFFLQFHFKMEK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.29
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SF3A2
Entrez GeneID
8175GeneBank Accession#
NM_007165Protein Accession#
NP_009096Gene Name
SF3A2
Gene Alias
PRP11, PRPF11, SAP62, SF3a66
Gene Description
splicing factor 3a, subunit 2, 66kDa
Omim ID
600796Gene Ontology
HyperlinkGene Summary
This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein. [provided by RefSeq
Other Designations
pre-mRNA splicing factor SF3A, subunit 2|spliceosome associated protein 62|splicing factor 3a, subunit 2
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Interactome
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Disease
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