SLC14A2 monoclonal antibody (M01), clone 3E7
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SLC14A2.
Immunogen
SLC14A2 (NP_009094, 40 a.a. ~ 128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ALPLLEMPEEKDLRSSNEDSHIVKIEKLNERSKRKDDGVAHRDSAGQRCICLSKAVGYLTGDMKEYRIWLKDKHLALQFIDWVLRGTAQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (72); Rat (72)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SLC14A2 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — SLC14A2
Entrez GeneID
8170GeneBank Accession#
NM_007163Protein Accession#
NP_009094Gene Name
SLC14A2
Gene Alias
FLJ16167, HUT2, MGC119566, MGC119567, UT-A2, UT2, UTA, UTR, hUT-A6
Gene Description
solute carrier family 14 (urea transporter), member 2
Omim ID
601611Gene Ontology
HyperlinkGene Summary
In mammalian cells, urea is the chief end-product of nitrogen catabolism and plays an important role in the urinary concentration mechanism. Thus, the plasma membrane of erythrocytes and some renal epithelial cells exhibit an elevated urea permeability that is mediated by highly selective urea transporters. In mammals, 2 urea transporters have been identified: the renal tubular urea transporter, UT2, and the erythrocyte urea transporter, UT11 (SLC14A1; MIM 111000).[supplied by OMIM
Other Designations
Urea transporter-2
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Interactome
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Disease
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