AKAP1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human AKAP1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human AKAP1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human AKAP1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — AKAP1
Entrez GeneID
8165GeneBank Accession#
AKAP1Gene Name
AKAP1
Gene Alias
AKAP, AKAP121, AKAP149, AKAP84, D-AKAP1, MGC1807, PRKA1, SAKAP84
Gene Description
A kinase (PRKA) anchor protein 1
Omim ID
602449Gene Ontology
HyperlinkGene Summary
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment. [provided by RefSeq
Other Designations
A-kinase anchor protein 1|A-kinase anchor protein, 149kD|dual-specificity A-kinase anchoring protein 1|protein kinase A anchoring protein 1|protein kinase A1|spermatid A-kinase anchor protein 84
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