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COIL 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00008161-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-COIL full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 63.47
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-COIL antibody (H00008161-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00008161-T01
    COIL transfected lysate.
    Western Blot
    QC Testing of H00008161-T01
    Lane 1: COIL transfected lysate ( 63.47 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 8161
  • Gene Name:
  • COIL
  • Gene Alias:
  • CLN80,p80-coilin
  • Gene Description:
  • coilin
  • Gene Summary:
  • The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq
  • Other Designations:
  • coilin p80
  • Related Disease
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