COIL (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of COIL transfected lysate using rabbit polyclonal anti-COIL and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-COIL.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (66); Rat (65)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of COIL transfected lysate using rabbit polyclonal anti-COIL and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-COIL.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-COIL (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-COIL (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — COIL
Entrez GeneID
8161Gene Name
COIL
Gene Alias
CLN80, p80-coilin
Gene Description
coilin
Omim ID
600272Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq
Other Designations
coilin p80
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Interactome
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Disease
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