COIL MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specifications
Product Description
Rabbit polyclonal antibody raised against a full-length human COIL protein.
Immunogen
COIL (NP_004636.1, 1 a.a. ~ 576 a.a) full-length human protein.
Sequence
MAASETVRLRLQFDYPPPATPHCTAFWLLVDLNRCRVVTDLISLIRQRFGFSSGAFLGLYLEGGLLPPAESARLVRDNDCLRVKLEERGVAENSVVISNGDINLSLRKAKKRAFQLEEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESDDQCLMSSSTPECAAGFLKTVGLFAGRGRPGPGLSSQTAGAAGWRRSGSNGGGQAPGASPSVSLPASLGRGWGREENLFSWKGAKGRGMRGRGRGRGHPVSCVVNRSTDNQRQQQLNDVVKNSSTIIQNPVETPKKDYSLLPLLAAAPQVGEKIAFKLLELTSSYSPDVSDYKEGRILSHNPETQQVDIEILSSLPALREPGKFDLVYHNENGAEVVEYAVTQESKITVFWKELIDPRLIIESPSNTSSTEPA
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (67)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of COIL expression in transfected 293T cell line (H00008161-T02) by COIL MaxPab polyclonal antibody.
Lane 1: COIL transfected lysate(62.6 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of COIL transfected lysate using anti-COIL MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with COIL purified MaxPab mouse polyclonal antibody (B01P) (H00008161-B01P). -
Gene Info — COIL
Entrez GeneID
8161GeneBank Accession#
NM_004645.2Protein Accession#
NP_004636.1Gene Name
COIL
Gene Alias
CLN80, p80-coilin
Gene Description
coilin
Omim ID
600272Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq
Other Designations
coilin p80
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Interactomes
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Diseases
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