GAN (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human GAN partial ORF ( NP_071324, 534 a.a. - 597 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
DLDTGTNYDYVREFKRSTGTWHHTKPLLPSDLRRTGCAALRIANCKLFRLQLQQGLFRIRVHSP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
32.78
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GAN
Entrez GeneID
8139GeneBank Accession#
NM_022041Protein Accession#
NP_071324Gene Name
GAN
Gene Alias
FLJ38059, GAN1, KLHL16
Gene Description
gigaxonin
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN). [provided by RefSeq
Other Designations
OTTHUMP00000174972|kelch-like protein 16
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Interactome
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Disease
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