GAN monoclonal antibody (M01), clone 4G7
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GAN is approximately 3ng/ml as a capture antibody.
Immunofluorescence
Immunofluorescence of monoclonal antibody to GAN on HeLa cell . [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (32.78 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GAN.
Immunogen
GAN (NP_071324, 534 a.a. ~ 597 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
DLDTGTNYDYVREFKRSTGTWHHTKPLLPSDLRRTGCAALRIANCKLFRLQLQQGLFRIRVHSP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (32.78 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GAN is approximately 3ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to GAN on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — GAN
Entrez GeneID
8139GeneBank Accession#
NM_022041Protein Accession#
NP_071324Gene Name
GAN
Gene Alias
FLJ38059, GAN1, KLHL16
Gene Description
gigaxonin
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN). [provided by RefSeq
Other Designations
OTTHUMP00000174972|kelch-like protein 16
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Interactome
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Disease
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