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Last updated: 2016/12/4

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CDK2AP1 rabbit monoclonal antibody

  • Catalog # : H00008099-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CDK2AP1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CDK2AP1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CDK2AP1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8099
  • Gene Name:
  • CDK2AP1
  • Gene Alias:
  • DOC1,DORC1,ST19,doc-1,p12DOC-1
  • Gene Description:
  • cyclin-dependent kinase 2 associated protein 1
  • Gene Summary:
  • The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes. [provided by RefSeq
  • Other Designations:
  • CDK2-associated protein 1,CDK2-associated protein 1,Deleted in oral cancer-1,cyclin-dependent kinase 2-associated protein 1,putative oral cancer suppressor
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