HMGA2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human HMGA2 partial ORF ( NP_003474, 1 a.a. - 92 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSARGEGAGQPSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSPSKAAQKKAEATGEKRPRGRPRKWPQQVVQKKP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
35.86
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — HMGA2
Entrez GeneID
8091GeneBank Accession#
NM_003483Protein Accession#
NP_003474Gene Name
HMGA2
Gene Alias
BABL, HMGI-C, HMGIC, LIPO, STQTL9
Gene Description
high mobility group AT-hook 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
High-mobility group protein HMGI-C|high-mobility group (nonhistone chromosomal) protein isoform I-C
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Interactome
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Disease
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