Western blot analysis of CSRP3 over-expressed 293 cell line, cotransfected with CSRP3 Validated Chimera RNAi ( Cat # H00008048-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with CSRP3 monoclonal antibody (M03), clone 6D2 (Cat # H00008048-M03 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq
LIM domain only 4,cardiac LIM domain protein,cardiac LIM protein,cysteine and glycine-rich protein 3,cysteine-rich protein 3,muscle LIM protein