NCOA4 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human NCOA4 partial ORF ( NP_005428, 505 a.a. - 614 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
EGSPKEVPGTEDRAGKQKFKSPMNTSWCSFNTADWVLPGKKMGNLSQLSSGEDKWLLRKKAQEVLLNSPLQEEHNFPPDHYGLPAVCDLFACMQLKVDKEKWLYRTPLQM
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Interspecies Antigen Sequence
Mouse (82); Rat (81)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NCOA4
Entrez GeneID
8031GeneBank Accession#
NM_005437Protein Accession#
NP_005428Gene Name
NCOA4
Gene Alias
ARA70, DKFZp762E1112, ELE1, PTC3, RFG
Gene Description
nuclear receptor coactivator 4
Gene Ontology
HyperlinkGene Summary
This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14. [provided by RefSeq
Other Designations
ELE1/ret TK|OTTHUMP00000019601|OTTHUMP00000019603|RET-activating gene ELE1
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Interactome
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Disease
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