STAM (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of STAM transfected lysate using mouse monoclonal anti-STAM and Protein A Magnetic Bead (U0007), and immunoblotted with mouse monoclonal anti-STAM.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of STAM transfected lysate using mouse monoclonal anti-STAM and Protein A Magnetic Bead (U0007), and immunoblotted with mouse monoclonal anti-STAM.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: mouse monoclonal anti-STAM (300 ug)
2. Antibody pair for WB: mouse monoclonal anti-STAM (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — STAM
Entrez GeneID
8027Gene Name
STAM
Gene Alias
DKFZp686J2352, STAM1
Gene Description
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
Omim ID
601899Gene Ontology
HyperlinkGene Summary
This gene was identified by the rapid tyrosine-phosphorylation of its product in response to cytokine stimulation. The encoded protein contains a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). This protein associates with JAK3 and JAK2 kinases via its ITAM region, and is phosphorylated by the JAK kinases upon cytokine stimulation, which suggests the function of this protein is as an adaptor molecule involved in the downstream signaling of cytokine receptors. HGS/HRS (hepatocyte grwoth factor-regulated tyrosine kinase substrate) has been found to bind and counteract the function of this protein. [provided by RefSeq
Other Designations
OTTHUMP00000019237|signal transducing adaptor molecule 1
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Interactome
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Pathway
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Disease
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