Products

Western Blot (Recombinant protein)

ELISA

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

NR4A3

Gene Alias

CHN, CSMF, MINOR, NOR1, TEC

Gene Description

nuclear receptor subfamily 4, group A, member 3

Omim ID

Gene Ontology

Gene Summary

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Four transcript variants encoding three distinct isoforms have been identified for this gene. [provided by RefSeq

Other Designations

OTTHUMP00000022775|OTTHUMP00000022776|chondrosarcoma, extraskeletal myxoid, fused to EWS|mitogen induced nuclear orphan receptor|neuron derived orphan receptor|translocated in extraskeletal chondrosarcoma