ARHGEF5 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ARHGEF5 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ARHGEF5 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ARHGEF5 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ARHGEF5
Entrez GeneID
7984GeneBank Accession#
ARHGEF5Gene Name
ARHGEF5
Gene Alias
DKFZp686N1969, GEF5, P60, TIM, TIM1
Gene Description
Rho guanine nucleotide exchange factor (GEF) 5
Omim ID
600888Gene Ontology
HyperlinkGene Summary
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq
Other Designations
guanine nucleotide regulatory protein TIM|rho guanine nucleotide exchange factor 5|transforming immortalized mammary oncogene
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Interactome
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Disease
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