EPM2A MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of EPM2A expression in transfected 293T cell line (H00007957-T02) by EPM2A MaxPab polyclonal antibody.
Lane 1: EPM2A transfected lysate(37.2 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of EPM2A transfected lysate using anti-EPM2A MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with EPM2A MaxPab mouse polyclonal antibody (B01) (H00007957-B01).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human EPM2A protein.
Immunogen
EPM2A (AAH70047.1, 1 a.a. ~ 331 a.a) full-length human protein.
Sequence
MRFRFGVVVPPAVAGARPELLVVGSRPELGRWEPRGAVRLRPAGTAAGDGALALQEPGLWLGEVELAAEEAAQDGAEPGRVDTFWYKFLKREPGGELSWEGNGPHHDRCCTYNENNLVDGVYCLPIGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFKTEWDIVQNSSGCNRYPEPMTPDTMIKLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAVCGWLQYVMGWNLRKVQYFLMAKRPAVYIDEEALARAQEDFFQKFGKVRSSVCSL
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (91)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of EPM2A expression in transfected 293T cell line (H00007957-T02) by EPM2A MaxPab polyclonal antibody.
Lane 1: EPM2A transfected lysate(37.2 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of EPM2A transfected lysate using anti-EPM2A MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with EPM2A MaxPab mouse polyclonal antibody (B01) (H00007957-B01). -
Gene Info — EPM2A
Entrez GeneID
7957GeneBank Accession#
BC070047.1Protein Accession#
AAH70047.1Gene Name
EPM2A
Gene Alias
EPM2, MELF
Gene Description
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
Gene Ontology
HyperlinkGene Summary
This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000017360|epilepsy, progressive myoclonus type 2, Lafora disease (laforin)|laforin
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Interactome
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Disease
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Publication Reference
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Lafora progressive myoclonus-epilepsy: Laforin targets malin to glycogen.
Sharmistha Mitra, Baozhi Chen, Peixiang Wang, Erin E Chown, Mathew Dear, Dikran R Guisso, Ummay Mariam, Jun Wu, Emrah Gumusgoz, Berge A Minassian.
Disease Models & Mechanisms 2023 Jan; 16(1):dmm049802.
Application：WB-Ti, Mouse , Mouse brain, Mouse heart, Mouse liver, Mouse muscle.
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Lafora progressive myoclonus-epilepsy: Laforin targets malin to glycogen.
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