TFEB (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human TFEB full-length ORF ( AAH32448, 1 a.a. - 476 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MASRIGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIGSNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSSSCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPTTSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPLLSTMSPEASKASSRRSSFSMEEGDVL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
78.10
Interspecies Antigen Sequence
Mouse (93); Rat (94)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TFEB
Entrez GeneID
7942GeneBank Accession#
BC032448Protein Accession#
AAH32448Gene Name
TFEB
Gene Alias
AlphaTFEB, TCFEB, bHLHe35
Gene Description
transcription factor EB
Omim ID
600744Gene Ontology
HyperlinkOther Designations
OTTHUMP00000043540|OTTHUMP00000043542|OTTHUMP00000071327|T-cell transcription factor EB
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Interactome
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Publication Reference
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An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis.
Yifeng Wang, Sumedha Gunewardena, Feng Li, David J Matye, Cheng Chen, Xiaojuan Chao, Taeyoon Jung, Yuxia Zhang, Maciej Czerwiński, Hong-Min Ni, Wen-Xing Ding, Tiangang Li.
Nature Communications 2020 Jul; 11(1):3612.
Application:EMSA, Human, Mouse, DNA probe.
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An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis.
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