HSD17B8 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of HSD17B8 transfected lysate using rabbit polyclonal anti-HSD17B8 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-HSD17B8.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (86); Rat (86)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of HSD17B8 transfected lysate using rabbit polyclonal anti-HSD17B8 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-HSD17B8.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-HSD17B8 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-HSD17B8 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — HSD17B8
Entrez GeneID
7923Gene Name
HSD17B8
Gene Alias
D6S2245E, FABG, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1, dJ1033B10.9
Gene Description
hydroxysteroid (17-beta) dehydrogenase 8
Omim ID
601417Gene Ontology
HyperlinkGene Summary
In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq
Other Designations
17-beta-HSD 8|17-beta-hydroxysteroid dehydrogenase 8|OTTHUMP00000029153|beta-ketoacyl-[acyl-carrier-protein] reductase-like|estradiol 17 beta-dehydrogenase 8|estrogen 17-oxidoreductase|short chain dehydrogenase/reductase family 30C, member 1
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Interactome
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Pathway
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Disease
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