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Last updated: 2016/10/23

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HSD17B8 rabbit monoclonal antibody

  • Catalog # : H00007923-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human HSD17B8 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human HSD17B8 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human HSD17B8 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 7923
  • Gene Name:
  • HSD17B8
  • Gene Alias:
  • D6S2245E,FABG,FABGL,H2-KE6,HKE6,KE6,RING2,SDR30C1,dJ1033B10.9
  • Gene Description:
  • hydroxysteroid (17-beta) dehydrogenase 8
  • Gene Summary:
  • In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq
  • Other Designations:
  • 17-beta-HSD 8,17-beta-hydroxysteroid dehydrogenase 8,OTTHUMP00000029153,beta-ketoacyl-[acyl-carrier-protein] reductase-like,estradiol 17 beta-dehydrogenase 8,estrogen 17-oxidoreductase,short chain dehydrogenase/reductase family 30C, member 1
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