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BAT1 rabbit monoclonal antibody

  • Catalog # : H00007919-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human BAT1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human BAT1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human BAT1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 7919
  • GeneBank Accession#:
  • BAT1
  • Gene Name:
  • BAT1
  • Gene Alias:
  • D6S81E,DDX39B,UAP56
  • Gene Description:
  • HLA-B associated transcript 1
  • Gene Summary:
  • This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and also plays an important role in mRNA export from the nucleus to the cytoplasm. A cluster of genes, BAT1-BAT5, is localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq
  • Other Designations:
  • 56 kDa U2AF65-associated protein,ATP-dependent RNA helicase p47,DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B,DEAD-box protein UAP56,OTTHUMP00000029228,OTTHUMP00000029229,OTTHUMP00000035591,OTTHUMP00000035963,OTTHUMP00000035964,OTTHUMP00000035965,OTTHUMP0000
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