ALDH5A1 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human ALDH5A1 protein.
Immunogen
ALDH5A1 (NP_001071.1, 1 a.a. ~ 535 a.a) full-length human protein.
Sequence
MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of ALDH5A1 expression in transfected 293T cell line (H00007915-T02) by ALDH5A1 MaxPab polyclonal antibody.
Lane 1: ALDH5A1 transfected lysate(57.20 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of ALDH5A1 transfected lysate using anti-ALDH5A1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with ALDH5A1 purified MaxPab mouse polyclonal antibody (B01P) (H00007915-B01P). -
Gene Info — ALDH5A1
Entrez GeneID
7915GeneBank Accession#
NM_001080.3Protein Accession#
NP_001071.1Gene Name
ALDH5A1
Gene Alias
SSADH, SSDH
Gene Description
aldehyde dehydrogenase 5 family, member A1
Gene Ontology
HyperlinkGene Summary
This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
NAD(+)-dependent succinic semialdehyde dehydrogenase|OTTHUMP00000016088|aldehyde dehydrogenase 5A1|mitochondrial succinate semialdehyde dehydrogenase|succinate-semialdehyde dehydrogenase
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Interactome
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Pathway
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Disease
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