SLBP monoclonal antibody (M01), clone 2C4-1C8
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More Files
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Western Blot (Cell lysate)
SLBP monoclonal antibody (M01), clone 2C4-1C8 Western Blot analysis of SLBP expression in Hela S3 NE( Cat # L013V3 ).
Immunofluorescence
Immunofluorescence of monoclonal antibody to SLBP on HeLa cell. [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (55.44 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant SLBP.
Immunogen
SLBP (AAH14908, 1 a.a. ~ 270 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MACRPRSPPRHQSRCDGDASPPSPARWSLGRKRRADGRRWRPEDAEEAEHRGAERRPESFTTPEGPKPRSRCSDWASAVEEDEMRTRVNKEMARYKRKLLINDFGRERKSSSGSSDSKESMSTVPADFETDESVLMRRQKQINYGKNTIAYDRYIKEVPRHLRQPGIHPKTPNKFKKYSRRSWDQQIKLWKVALHFWDPPAEEGCDLQEIHPVDLESAESSSEPQTSSQDDFDVYSGTPTKVRHMDSQVEDEFDLEACLTEPLRDFSAMS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (86)
Isotype
IgG2a kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (55.44 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
SLBP monoclonal antibody (M01), clone 2C4-1C8 Western Blot analysis of SLBP expression in Hela S3 NE( Cat # L013V3 ).Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to SLBP on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — SLBP
Entrez GeneID
7884GeneBank Accession#
BC014908Protein Accession#
AAH14908Gene Name
SLBP
Gene Alias
HBP
Gene Description
stem-loop binding protein
Omim ID
602422Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1. [provided by RefSeq
Other Designations
OTTHUMP00000113498|hairpin binding protein, histone|histone binding protein|histone stem-loop binding protein|stem-loop (histone) binding protein
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Interactome
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Publication Reference
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CNOT6 regulates a novel pattern of mRNA deadenylation during oocyte meiotic maturation.
Vieux KF, Clarke HJ.
Scientific Reports 2018 May; 8(1):6812.
Application：WB, Mouse, Oocytes.
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Destabilization of CDC6 upon DNA damage is dependent on neddylation but independent of Cullin E3 ligases.
Tan CY, Hagen T.
The International Journal of Biochemistry & Cell Biology 2013 Jul; 45(7):1489.
Application：WB-Tr, Human, HEK 293 cells.
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CNOT6 regulates a novel pattern of mRNA deadenylation during oocyte meiotic maturation.
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