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Last updated: 2017/2/19

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KCNAB1 rabbit monoclonal antibody

  • Catalog # : H00007881-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human KCNAB1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human KCNAB1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human KCNAB1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7881
  • Gene Name:
  • KCNAB1
  • Gene Alias:
  • AKR6A3,KCNA1B,KV-BETA-1,Kvb1.3,hKvBeta3,hKvb3
  • Gene Description:
  • potassium voltage-gated channel, shaker-related subfamily, beta member 1
  • Gene Summary:
  • Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq
  • Other Designations:
  • potassium channel beta 3 chain,potassium channel beta3 subunit,potassium channel shaker chain beta 1a,potassium voltage-gated channel beta subunit,voltage-gated potassium channel beta-1 subunit
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