RAB7 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-RAB7 full-length
Host
Human
Theoretical MW (kDa)
23.5
Interspecies Antigen Sequence
Mouse (100); Rat (99)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-RAB7 antibody (H00007879-D01P) by Western Blots.
SDS-PAGE Gel
RAB7A transfected lysate.
Western Blot
Lane 1: RAB7A transfected lysate ( 23.50 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — RAB7A
Entrez GeneID
7879GeneBank Accession#
NM_004637Protein Accession#
NP_004628.4Gene Name
RAB7A
Gene Alias
FLJ20819, PRO2706, RAB7
Gene Description
RAB7A, member RAS oncogene family
Gene Ontology
HyperlinkGene Summary
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq
Other Designations
RAB7, member RAS oncogene family|Ras-associated protein RAB7
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Interactome
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Disease
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