RAB7 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human RAB7 full-length ORF ( NP_004628.4, 1 a.a. - 207 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
49.9
Interspecies Antigen Sequence
Mouse (100); Rat (99)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — RAB7A
Entrez GeneID
7879GeneBank Accession#
NM_004637.5Protein Accession#
NP_004628.4Gene Name
RAB7A
Gene Alias
FLJ20819, PRO2706, RAB7
Gene Description
RAB7A, member RAS oncogene family
Gene Ontology
HyperlinkGene Summary
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq
Other Designations
RAB7, member RAS oncogene family|Ras-associated protein RAB7
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Interactome
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Disease
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