IL1R2 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human IL1R2 protein.
Immunogen
IL1R2 (NP_004624.1, 1 a.a. ~ 398 a.a) full-length human protein.
Sequence
MLRLYVLVMGVSAFTLQPAAHTGAARSCRFRGRHYKREFRLEGEPVALRCPQVPYWLWASVSPRINLTWHKNDSARTVPGEEETRMWAQDGALWLLPALQEDSGTYVCTTRNASYCDKMSIELRVFENTDAFLPFISYPQILTLSTSGVLVCPDLSEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCVLTFAHEGQQYNITRSIELRIKKKKEETIPVIISPLKTISASLGSRLTIPCKVFLGTGTPLTTMLWWTANDTHIESAYPGGRVTEGPRQEYSENNENYIEVPLIFDPVTREDLHMDFKCVVHNTLSFQTLRTTVKEASSTFSWGIVLAPLSLAFLVLGGIWMHRRCKHRTGKADGLTVLWPHHQDFQSYPK
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and IL1R2 expressing 293 cells (Green) using IL1R2 purified MaxPab mouse polyclonal antibody.Western Blot (Tissue lysate)
IL1R2 MaxPab polyclonal antibody. Western Blot analysis of IL1R2 expression in human kidney.Western Blot (Cell lysate)
IL1R2 MaxPab polyclonal antibody. Western Blot analysis of IL1R2 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of IL1R2 expression in transfected 293T cell line (H00007850-T01) by IL1R2 MaxPab polyclonal antibody.
Lane 1: IL1R2 transfected lysate(43.78 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — IL1R2
Entrez GeneID
7850GeneBank Accession#
NM_004633.3Protein Accession#
NP_004624.1Gene Name
IL1R2
Gene Alias
CD121b, IL1RB, MGC47725
Gene Description
interleukin 1 receptor, type II
Omim ID
147811Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq
Other Designations
antigen CDw121b|type II interleukin-1 receptor, beta
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Interactome
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Pathway
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Disease
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