PXDN DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human PXDN DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — PXDN
Entrez GeneID
7837GeneBank Accession#
BC140295.1Protein Accession#
AAI40296.1Gene Name
PXDN
Gene Alias
D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN, VPO
Gene Description
peroxidasin homolog (Drosophila)
Omim ID
605158Gene Ontology
HyperlinkGene Summary
Drosophila peroxidasin is an extracellular matrix-associated peroxidase (Horikoshi et al., 1999 [PubMed 10441517]). It is expressed exclusively in hemocytes derived from head mesoderm at a very early stage of differentiation. Peroxidasin exists as a homotrimer with a unique hybrid structure that combines an enzymatically functional peroxidase domain with motifs that are typically found in extracellular matrix-associated proteins. It is a secreted protein that contains a secretory recognition sequence at its N terminus. Peroxidasin catalyzes hydrogen peroxide-driven radioiodination, oxidations, and the formation of dityrosine in vitro. It is also thought to function in extracellular matrix consolidation, phagocytosis, and defense.[supplied by OMIM
Other Designations
p53-responsive gene 2|peroxidasin homolog
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Interactome
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Disease
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