NPHS2 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Tissue lysate)
NPHS2 MaxPab rabbit polyclonal antibody. Western Blot analysis of NPHS2 expression in mouse kidney.
Western Blot (Transfected lysate)
Western Blot analysis of NPHS2 expression in transfected 293T cell line (H00007827-T02) by NPHS2 MaxPab polyclonal antibody.
Lane 1: NPHS2 transfected lysate(34.40 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of NPHS2 transfected lysate using anti-NPHS2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with NPHS2 purified MaxPab mouse polyclonal antibody (B01P) (H00007827-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human NPHS2 protein.
Immunogen
NPHS2 (AAH29141.1, 1 a.a. ~ 315 a.a) full-length human protein.
Sequence
MERRARSSSRESRGRGGRTPHKENKRAKAERSGGGRGRQEAGPEPSGSGRAGTPGEPRAPAATVVDVDEVRGSGEEGTEVVALLESERPEEGTKSSGLGACEWLLVLISLLFIIMTFPFSIWFCVKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEVALDSVTCIWGIKVERIEIKDVRLPAGLQHSLAVEAEAQRQAKVRMIAAEAEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTEKPSTVVLPLPFDLLNCLSSPSNRTQGSLPFPSPSKPVEPLNPKKKDSPML
Host
Rabbit
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (80)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
NPHS2 MaxPab rabbit polyclonal antibody. Western Blot analysis of NPHS2 expression in mouse kidney.Western Blot (Transfected lysate)
Western Blot analysis of NPHS2 expression in transfected 293T cell line (H00007827-T02) by NPHS2 MaxPab polyclonal antibody.
Lane 1: NPHS2 transfected lysate(34.40 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of NPHS2 transfected lysate using anti-NPHS2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with NPHS2 purified MaxPab mouse polyclonal antibody (B01P) (H00007827-B01P). -
Gene Info — NPHS2
Entrez GeneID
7827GeneBank Accession#
BC029141Protein Accession#
AAH29141.1Gene Name
NPHS2
Gene Alias
PDCN, SRN1
Gene Description
nephrosis 2, idiopathic, steroid-resistant (podocin)
Gene Ontology
HyperlinkGene Summary
This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000033186|podocin
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Interactome
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Disease
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