Products

Western Blot (Transfected lysate)

Immunofluorescence (Transfected cell)

Flow Cytometry (Transfected cell)

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

PTP4A1

Gene Alias

DKFZp779M0721, HH72, PRL-1, PRL1, PTP(CAAX1), PTPCAAX1

Gene Description

protein tyrosine phosphatase type IVA, member 1

Omim ID

Gene Ontology

Gene Summary

The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. [provided by RefSeq

Other Designations

OTTHUMP00000016675|Protein tyrosine phosphatase IVA1|protein tyrosine phosphatase type IVA protein 1