PTP4A1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PTP4A1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PTP4A1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PTP4A1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PTP4A1
Entrez GeneID
7803GeneBank Accession#
PTP4A1Gene Name
PTP4A1
Gene Alias
DKFZp779M0721, HH72, PRL-1, PRL1, PTP(CAAX1), PTPCAAX1
Gene Description
protein tyrosine phosphatase type IVA, member 1
Omim ID
601585Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. [provided by RefSeq
Other Designations
OTTHUMP00000016675|Protein tyrosine phosphatase IVA1|protein tyrosine phosphatase type IVA protein 1
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