PRDM2 (Human) Recombinant Protein (Q01)
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More Files
- More Functions
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Specification
Product Description
Human PRDM2 partial ORF ( NP_036363, 1606 a.a. - 1705 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
KTSRSLHVRVQKSKAVLQSKSTLASKKRTDRFNIKSRERSGGPVTRSLQLAAAADLSENKREDGSAKQELKDFSYSLRLASRCSPPAAPYITRQYRKVKA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (82)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PRDM2
Entrez GeneID
7799GeneBank Accession#
NM_012231Protein Accession#
NP_036363Gene Name
PRDM2
Gene Alias
HUMHOXY1, KMT8, MTB-ZF, RIZ, RIZ1, RIZ2
Gene Description
PR domain containing 2, with ZNF domain
Omim ID
601196Gene Ontology
HyperlinkGene Summary
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
GATA-3 binding protein G3B|MTE-binding protein|OTTHUMP00000009642|OTTHUMP00000009687|retinoblastoma protein-binding zinc finger protein|retinoblastoma protein-interacting zinc finger protein|zinc-finger DNA-binding protein
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Interactome
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Disease
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