Products

Western Blot (Recombinant protein)

ELISA

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

PRDM2

Gene Alias

HUMHOXY1, KMT8, MTB-ZF, RIZ, RIZ1, RIZ2

Gene Description

PR domain containing 2, with ZNF domain

Omim ID

Gene Ontology

Gene Summary

This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Other Designations

GATA-3 binding protein G3B|MTE-binding protein|OTTHUMP00000009642|OTTHUMP00000009687|retinoblastoma protein-binding zinc finger protein|retinoblastoma protein-interacting zinc finger protein|zinc-finger DNA-binding protein