ZYX 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
ZYX transfected lysate.
Western Blot
Lane 1: ZYX transfected lysate ( 61.30 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ZYX full-length
Host
Human
Theoretical MW (kDa)
61.3
Interspecies Antigen Sequence
Mouse (86); Rat (85)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ZYX antibody (H00007791-B01P) by Western Blots.
SDS-PAGE Gel
ZYX transfected lysate.
Western Blot
Lane 1: ZYX transfected lysate ( 61.30 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ZYX
Entrez GeneID
7791GeneBank Accession#
NM_001010972.1Protein Accession#
NP_001010972.1Gene Name
ZYX
Gene Alias
ESP-2, HED-2
Gene Description
zyxin
Omim ID
602002Gene Ontology
HyperlinkGene Summary
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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