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Last updated: 2016/10/23
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ZYX purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00007791-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human ZYX protein.
  • Immunogen:
  • ZYX (NP_001010972.1, 1 a.a. ~ 572 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of ZYX expression in transfected 293T cell line (H00007791-T02) by ZYX MaxPab polyclonal antibody.

    Lane 1: ZYX transfected lysate(62.92 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
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  • Gene Information
  • Entrez GeneID:
  • 7791
  • Gene Name:
  • ZYX
  • Gene Alias:
  • ESP-2,HED-2
  • Gene Description:
  • zyxin
  • Gene Summary:
  • Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq
  • Other Designations:
  • -
  • Gene Pathway
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