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Last updated: 2017/12/17

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MAP3K12 Pre-design Chimera RNAi

  • Catalog # : H00007786-R03
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  • Specification
  • Product Description:
  • Homo sapiens mitogen-activated protein kinase kinase kinase 12 (MAP3K12), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_006301
  • Target Region:
  • Coding sequence
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 7786
  • Gene Name:
  • MAP3K12
  • Gene Alias:
  • DLK,MUK,ZPK,ZPKP1
  • Gene Description:
  • mitogen-activated protein kinase kinase kinase 12
  • Gene Summary:
  • The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. [provided by RefSeq
  • Other Designations:
  • dual leucine zipper kinase DLK,leucine zipper protein kinase,protein kinase MUK,zipper protein kinase
  • Gene Pathway
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