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ZP2 Pre-design Chimera RNAi

  • Catalog # : H00007783-R02
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  • Specification
  • Product Description:
  • Homo sapiens zona pellucida glycoprotein 2 (sperm receptor) (ZP2), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_003460
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 7783
  • Gene Name:
  • ZP2
  • Gene Alias:
  • ZPA
  • Gene Description:
  • zona pellucida glycoprotein 2 (sperm receptor)
  • Gene Summary:
  • The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. [provided by RefSeq
  • Other Designations:
  • zona pellucida glycoprotein 2,zona pellucida protein A,zona pellucida sperm-binding protein 2
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